Pilot study investigating diagnostic utility of serum MMP-1 and TGF-β1 in asthma in 'real world' clinical practice in India.
Aswani PrabhaKomarla Sundararaja LokeshSindaghatta Krishnarao ChayaBiligere Siddaiah JayarajSowmya MalamardiSubbaRao V MadhunapantulaSarah C BeckMamidipudi Thirumala KrishnaMahesh Padukudru AnandPublished in: Journal of clinical pathology (2021)
This pilot study showed that serum MMP-1 and TGF-β1 levels are elevated in chronic asthma and may serve as a useful adjunct in differentiating moderate from severe asthma. A large multicentre study in well characterised cohort of asthmatics is warranted to investigate their role in diagnosis and therapeutic monitoring.