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FCER2 T2206C variant associated with FENO levels in asthmatic children using inhaled corticosteroids: The PACMAN study.

Leila KarimiSusanne J H VijverbergNiloufar FarzanMohsen GhanbariKatia M C VerhammeAnke H Maitland-van der Zee
Published in: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology (2019)
Our results showed that the FCER2 T2206C variant was significantly associated with lower FENO levels in carriers of the G allele. Nevertheless, this SNP contributed little to the variability in FENO levels in this patient population. Our findings contribute to the present knowledge on FENO in asthmatic children; however, future replication studies are required to establish the role of this gene in relation to FENO.
Keyphrases
  • young adults
  • genome wide
  • healthcare
  • lung function
  • cystic fibrosis
  • case report
  • gene expression
  • current status
  • transcription factor