Elucidating regulatory processes of intense physical activity by multi-omics analysis.

Ernesto S NakayasuMarina A GritsenkoYoung-Mo KimJennifer E KyleKelly G StrattonCarrie D NicoraNathalie MunozKathleen M NavarroDaniel ClaborneYuqian GaoKarl K WeitzVanessa L PaurusKent J BloodsworthKelsey A AllenLisa M BramerFernando MontesKathleen A ClarkGrant TietjeJustin TeeguardenKristin E Burnum-Johnson

Published in: Military Medical Research (2023)

This study shows simultaneous regulatory signatures in biofluids indicative of homeostatic maintenance during intense physical activity with possible effects on increased infection susceptibility, suggesting that caution against respiratory diseases could benefit workers on highly physical demanding jobs.

Keyphrases

physical activity
transcription factor
body mass index
mental health
single cell
gene expression
sleep quality
depressive symptoms
dna methylation
respiratory tract