Hydatidiform mole diagnostics using circulating gestational trophoblasts isolated from maternal blood.

Lone Sunde Ripudaman Singh Katarina Ravn Palle Schelde Estrid Staehr Hansen Niels UldbjergIsa NiemannLotte Hatt

Published in: Molecular genetics & genomic medicine (2020)

Our results show that it is possible to isolate and analyze circulating gestational trophoblasts originating in a pregnancy without maternal nuclear genome. For diagnosing gestational trophoblastic diseases, genotyping circulating gestational trophoblasts appears to be superior to analysis of cell-free DNA.

Keyphrases

weight gain
pregnancy outcomes
birth weight
pregnant women
body mass index
gestational age
genome wide
weight loss
preterm birth