Exogenous Spermidine Alleviates Diabetic Myocardial Fibrosis Via Suppressing Inflammation and Pyroptosis in db/db Mice.

Can Wei Jiyu Xu Yong Liu Javeria Qadir Shumin Zhang Hui Yuan

Published in: Balkan medical journal (2023)

Based on our findings, SPD may have potential applications in protecting against the deterioration of cardiac function in patients with DCM due to a significant new mechanism for diabetic myocardial fibrosis that we discovered.

Keyphrases

left ventricular
type diabetes
wound healing
oxidative stress
signaling pathway
high fat diet induced
insulin resistance
human health
skeletal muscle
risk assessment
adipose tissue
atrial fibrillation