Higher prevalence of splenic artery aneurysms in hereditary hemorrhagic telangiectasia: Vascular implications and risk factors.

Jacques SellierCarma KaramAlain BeauchetAxel DallongevilleStephen BinsseSandra BlivetIsabelle Bourgault-VilladaPhilippe CharronThierry ChinetMélanie EyriesCarole FagnouJérome LesniakGilles LesurJérome LucasAgnès Nicod-TranAugustin OzanneAsurélien PalmyreFlorent SoubrierMostafa El HajjamPascal Lacombe

Published in: PloS one (2020)

We found a 4.57 higher rate of SAA in HHT patients without evidence of splenic high output related disease or increased CVRF. These results suggest the presence of a vascular intrinsic involvement. It should lead to screening all HHT patients for SAA. The vasculopathy hypothesis could require a change in management as screening of all systemic arteries and even the aorta and to further research in the field.

Keyphrases

risk factors
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
prognostic factors
coronary artery
pulmonary hypertension
blood flow