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Is mechanical power an under-recognised entity within the preterm lung?

David Gerald TingayHannah NaiduHamish D TingayPrue M Pereira-FantiniMartin C J KneyberTobias H Becher
Published in: Intensive care medicine experimental (2023)
In our hypothesis-generating dataset, changes in mechanical power were evident during clinically important states for the preterm lung, specifically transition to air-breathing, changes in aeration and surfactant administration. Future preclinical studies using ventilation strategies designed to highlight different types of lung injury, including volu-, baro- and ergotrauma, are needed to test our hypothesis.
Keyphrases
  • low birth weight
  • preterm birth
  • gestational age
  • preterm infants
  • stem cells
  • respiratory failure
  • mechanical ventilation
  • mesenchymal stem cells