Control of the extracellular matrix by hypoxic lymphatic endothelial cells: Impact on the progression of lymphedema?

Joerg WiltingGunther FelmererJürgen Becker

Published in: Developmental dynamics : an official publication of the American Association of Anatomists (2022)

Overall, hypoxia results in the picture of a dysregulated ECM production of LECs, which might be partly responsible for the progression of fibrosclerosis in lymphedema.

Keyphrases

extracellular matrix
endothelial cells
lymph node
high glucose