Comparison of conventional cytomorphology, flow cytometry immunophenotyping, and automated cell counting of CSF for detection of CNS involvement in acute lymphoblastic leukemia.

José Carlos Jaime-PérezM F Borrego-LópezR A Jiménez-CastilloN Méndez-RamírezR Salazar-RiojasL T FernándezD Gómez-Almaguer

Published in: International journal of laboratory hematology (2017)

Flow cytometry immunophenotyping complements conventional cytospin analysis for detection of lymphoblasts in the CSF of ALL patients at any clinical stage.

Keyphrases

flow cytometry
acute lymphoblastic leukemia
loop mediated isothermal amplification
real time pcr
label free
machine learning
single cell
deep learning
cell therapy
stem cells
allogeneic hematopoietic stem cell transplantation
cerebrospinal fluid
bone marrow
clinical evaluation