Dynamic Loading-A New Marker for Abdominal Aneurysm Growth?
John FriesenLucas SteinFarzin AdiliPeter F PelzPublished in: Medicina (Kaunas, Lithuania) (2023)
The growing possibilities of non-invasive heart rate and blood pressure measurement with mobile devices allow vital data to be continuously collected and used to assess patients' health status. When it comes to the risk assessment of abdominal aortic aneurysms (AAA), the continuous tracking of blood pressure and heart rate could enable a more patient-specific approach. The use of a load function and an energy function, with continuous blood pressure, heart rate, and aneurysm stiffness as input parameters, can quantify dynamic load on AAA. We hypothesise that these load functions correlate with aneurysm growth and outline a possible study procedure in which the hypothesis could be tested for validity. Subsequently, uncertainty quantification of input quantities and derived quantities is performed.
Keyphrases
- heart rate
- blood pressure
- heart rate variability
- coronary artery
- risk assessment
- hypertensive patients
- end stage renal disease
- abdominal aortic
- ejection fraction
- newly diagnosed
- chronic kidney disease
- abdominal aortic aneurysm
- peritoneal dialysis
- adipose tissue
- minimally invasive
- human health
- big data
- electronic health record
- heavy metals
- metabolic syndrome
- machine learning
- climate change
- insulin resistance