Timing of Pubertal Onset in Girls and Boys With Constitutional Delay.
Elfa Jonsdottir-LewisAmalia FeldRyan CiarloErica DenhoffHenry A FeldmanYee-Ming ChanPublished in: The Journal of clinical endocrinology and metabolism (2021)
The broad range of ages at pubertal entry for children with constitutional delay challenges the concept that constitutional delay is merely an extreme of normal variation. Discussions with patients and families about management should consider the possibility that some children may need to wait years after presentation until puberty starts.