The CpG island methylator phenotype increases the risk of high-grade squamous intraepithelial lesions and cervical cancer.
Jaqueline Loaeza-LoaezaBerenice Illades-AguiarOscar Del Moral-HernándezYaneth Castro-CoronelMarco A Leyva-VázquezRoberto Dircio-MaldonadoJulio Ortiz-OrtizDaniel Hernández-SoteloPublished in: Clinical epigenetics (2022)
We found that CIMP high was significantly associated with HSIL and CC risk. These results could indicate that CIMP together with HR-HPV infection and other factors participates in the development of HSIL and CC.
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