Are high- and low-molecular-weight sensitizing agents associated with different clinical phenotypes of occupational asthma?

Olivier VandenplasJulien GodetLaura HurdubaeaCatherine RifflartHille SuojalehtoMarta WiszniewskaXavier MunozJoaquin SastrePavlina KlusackovaVicky MooreRolf MergetDonatella TaliniCecilie SvanesPaola MasonMarco dell'OmoPaul CullinanGianna MoscatoSantiago QuirceJennifer HoyleDavid L ShersonPaula KauppiAlexandra PreisserNicolas MeyerFrédéric de Blaynull null

Published in: Allergy (2018)

This large cohort study describes distinct phenotypic profiles in OA caused by HMW and LMW agents. There is a need to further explore differences in underlying pathophysiological pathways and outcome after environmental interventions.

Keyphrases

chronic obstructive pulmonary disease
lung function
physical activity
knee osteoarthritis
human health
risk assessment
life cycle