Metabolite Biomarkers of CKD Progression in Children.

Michelle R DenburgYunwen XuAlison G AbrahamJosef CoreshJingsha ChenMorgan E GramsHarold I FeldmanPaul L KimmelCasey M RebholzEugene P RheeRamachandran S VasanBradley A WaradySusan L Furthnull null

Published in: Clinical journal of the American Society of Nephrology : CJASN (2022)

Untargeted plasma metabolomic profiling facilitated discovery of novel metabolite associations with CKD progression in children that were independent of established clinical predictors and highlight the role of select biologic pathways.

Keyphrases

chronic kidney disease
young adults
rheumatoid arthritis
mass spectrometry
small molecule
high throughput
simultaneous determination
solid phase extraction