Monoamine neurotransmitters in early epileptic encephalopathies: New insights into pathophysiology and therapy.

Natalia Alexandra Julia-PalaciosCristina Molina-AnguitaMaría Sigatulina BondarenkoElisenda Cortés-SaladelafontJavier AparicioDaniel CuadrasGabriella HorvathCarmen FonsRafael ArtuchÁngeles García-Cazorlanull null

Published in: Developmental medicine and child neurology (2022)

5-Hydroxyindoleacetic acid homeostasis is especially vulnerable in patients with epileptic encephalopathy/developmental and epileptic encephalopathy. Age of seizure onset and duration of epilepsy are determinants of neurotransmitter depletion.

Keyphrases

early onset
temporal lobe epilepsy
stem cells
mesenchymal stem cells
cell therapy