Advances in nanotechnology-based platforms for survivin-targeted drug discovery.
Rosemol GeorgeStephanie HehlgansMaximillian FleischmannClaus Michael RödelEmmanouil FokasFranz RödelPublished in: Expert opinion on drug discovery (2022)
Novel therapeutic approaches include the use of biocompatible nanoformulations carrying gene silencing or drug molecules to directly or indirectly target proteins, allow for a more precise and controlled delivery of survivin therapeutics. Moreover, surface modification of these nanocarriers may result in a tumor entity-specific delivery. Therefore, nanomedicine exploiting survivin-tailored strategies in a multimodal background is considered the way forward to enhance the development of future personalized medicine.