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Frequent birth-and-death events throughout perforin-1 evolution.

Miguel Araujo-VocesVíctor Quesada
Published in: BMC evolutionary biology (2020)
The assisted annotation of new genomic assemblies shows complex patterns of birth-and-death events in the evolution of perforin. These events include duplication/pseudogenization in mammals, multiple amplifications and losses in reptiles and fishes and at least one case of partial duplication with a novel start codon in fishes.
Keyphrases
  • gestational age
  • gene expression
  • dna methylation
  • rna seq