Frequent birth-and-death events throughout perforin-1 evolution.
Miguel Araujo-VocesVíctor QuesadaPublished in: BMC evolutionary biology (2020)
The assisted annotation of new genomic assemblies shows complex patterns of birth-and-death events in the evolution of perforin. These events include duplication/pseudogenization in mammals, multiple amplifications and losses in reptiles and fishes and at least one case of partial duplication with a novel start codon in fishes.