Pathoarchitectonics of the cerebral cortex in chorea-acanthocytosis and Huntington's disease.
Jia LiuH HeinsenL T GrinbergE AlhoE AmaroC A PasqualucciU RübK SeidelW den DunnenT ArzbergerC SchmitzM C KiesslingB BaderAdrian DanekPublished in: Neuropathology and applied neurobiology (2018)
ChAc is a neurodegenerative disease with distinct cortical neurodegeneration. The hypertrophy of the peripheral neuropil space of minicolumns with coarse vertical striation was characteristic of ChAc. The role of astroglia in the pathogenesis of this disorder remains to be elucidated.