Computed tomographic findings in TBX4 mutation: a common cause of severe pulmonary artery hypertension in children.
Helio V Neves da SilvaJason P WeinmanErin K EnglundRobin R DeterdingDunbar D IvyLorna P BrownePublished in: Pediatric radiology (2024)
TBX4 mutations have distinct imaging phenotypes in pediatric patients with PAH. Compared to patients without this mutation, patients with TBX-4 genes typically present with peripheral or subpleural irregularity, cystic lucencies, and linear or reticular opacity.
Keyphrases
- pulmonary artery
- coronary artery
- pulmonary hypertension
- end stage renal disease
- pulmonary arterial hypertension
- blood pressure
- ejection fraction
- newly diagnosed
- young adults
- high resolution
- peritoneal dialysis
- prognostic factors
- genome wide
- mass spectrometry
- transcription factor
- genome wide identification
- arterial hypertension
- bioinformatics analysis