Comparative analysis of the phototoxicity induced by BRAF inhibitors and alleviation through antioxidants.

Markus Vincent HepptBenjamin M Clanner-EngelshofenEnklajd MarselaAnja WesselyClaudia KammerbauerBernhard PrzybillaLars E FrenchCarola BerkingMarkus Reinholz

Published in: Photodermatology, photoimmunology & photomedicine (2019)

Our study confirms that most of the BRAF inhibitors exhibited a considerable phototoxic potential, predominantly after exposure to UVA. GSH may help treat and prevent the phototoxicity induced by vemurafenib.

Keyphrases

metastatic colorectal cancer

wild type

climate change