Login / Signup

Effects of in vitro vitamin D treatment on function of T cells and autophagy mechanisms in high-fat diet-induced obese mice.

Min Su KangChan Yoon ParkGa Young LeeDa Hye ChoSo Jeong KimSung Nim Han
Published in: Nutrition research and practice (2021)
Our findings suggest that diet-induced obesity may impair the function and inhibit autophagy of T cells, possibly leading to the dysregulation of T cell homeostasis, which may be behind the aggravation of inflammation commonly observed in obesity.
Keyphrases
  • high fat diet induced
  • insulin resistance
  • oxidative stress
  • cell death
  • endoplasmic reticulum stress
  • metabolic syndrome
  • signaling pathway
  • adipose tissue
  • type diabetes
  • weight loss
  • weight gain
  • body mass index