Neonatal metabolome of cesarean section and risk of childhood asthma.

Gözde GürdenizMadeleine ErnstDaniela RagoMin KimJulie CourraudJakob StokholmKlaus BønnelykkeAnders BjörkbomUrvish TrivediSøren J SørensenSusanne B PedersenDavid HougaardMorten RasmussenArieh S CohenHans BisgaardBo Chawes

Published in: The European respiratory journal (2021)

These findings propose that CS is programming the risk of childhood asthma through perturbed immune responses and gut microbial colonization patterns reflected in the blood metabolome at birth.

Keyphrases

chronic obstructive pulmonary disease
immune response
lung function
allergic rhinitis

early life
childhood cancer
microbial community

air pollution
toll like receptor
pregnant women

inflammatory response
pregnancy outcomes
preterm birth