High-Throughput Sequencing and Exploration of the lncRNA-circRNA-miRNA-mRNA Network in Type 2 Diabetes Mellitus.

Fang Yang Yang Chen Zhiqiang Xue Yaogai Lv Li Shen Kexin Li Pingping Zheng Pan PanTianyu FengLina Jin Yan Yao

Published in: BioMed research international (2020)

This study is the first study to explore the molecular mechanisms of lncRNA and circRNA in T2DM through the ceRNA network cofounded by lncRNA and circRNA. Our study provides a novel insight into the T2DM from the ceRNA regulatory network.

Keyphrases

long non coding rna
type diabetes
metabolic syndrome
adipose tissue
high throughput sequencing
skeletal muscle
weight loss
glycemic control