Enhanced Antibacterial Activity of Silver Nanoparticles Combined with Hydrogen Peroxide Against Multidrug-Resistant Pathogens Isolated from Dairy Farms and Beef Slaughterhouses in Egypt.
Fatma A El-GoharyLina Jamil M Abdel-HafezAmira I ZakariaRadwa Reda ShataAmin TahounAmany El-MleehEman A Abo ElfadlEhab Kotb ElmahallawyPublished in: Infection and drug resistance (2020)
The present data report high prevalence rates of MDR pathogens in dairy farms and abattoirs. More importantly, AgNPs-H2O2 exerted broad-spectrum bactericidal activity toward MDR bacterial strains, suggesting their promising usage as safe, ecofriendly, cost-effective antibacterial agents. To our knowledge, this study is a pioneer in investigating the potential alternative antimicrobial role of silver nanoparticles for control of multiple drug-resistant pathogens in Egypt.
Keyphrases
- silver nanoparticles
- multidrug resistant
- gram negative
- drug resistant
- hydrogen peroxide
- acinetobacter baumannii
- klebsiella pneumoniae
- nitric oxide
- escherichia coli
- staphylococcus aureus
- healthcare
- risk factors
- antimicrobial resistance
- electronic health record
- big data
- machine learning
- pseudomonas aeruginosa
- cystic fibrosis
- risk assessment