Comparative 3D genome architecture in vertebrates.

Diyan LiMengnan HeQianzi TangShilin TianJiaman ZhangYan LiDanyang WangLong JinChunyou NingWei ZhuSilu HuKeren LongJideng MaJing LiuZhihua ZhangMingzhou Li

Published in: BMC biology (2022)

Our analysis uncovers organizational features that appear to determine the conservation and transcriptional regulation of functional genes across species. These findings can guide ongoing investigations of genome evolution by extending our understanding of the mechanisms shaping genome architecture.

Keyphrases

genome wide
gene expression
bioinformatics analysis
genome wide analysis