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Natural polyphenolic coffee extract administration relieves chronic nociplastic pain in a reserpine-induced fibromyalgia-like female mouse model.

Rubén Toledano-MartosAnna Bagó-MasMeritxell DeulofeuJudit HomsNúria FiolEnrique VerdúNúria Fiol
Published in: Brain and behavior (2024)
Thus, the CE may be a potential pharmacological treatment suitable to relieve nociplastic pain responses characteristic of FM.
Keyphrases
  • chronic pain
  • mouse model
  • pain management
  • neuropathic pain
  • high glucose
  • oxidative stress
  • drug induced
  • endothelial cells
  • combination therapy