Radiomic signatures from T2W and DWI MRI are predictive of tumour hypoxia in colorectal liver metastases.
Zuhir BodalalNino BogveradzeLeon C Ter BeekJose G van den BergJoyce SandersIngrid HoflandStefano TrebeschiKevin B W Groot LipmanKoen StorckEun Kyoung HongNatalya LebedyevaMonique MaasRegina G H Beets-TanFernando Gómez MuñozIeva KurilovaPublished in: Insights into imaging (2023)
Hypoxia is a negative prognostic biomarker in colorectal cancer. Hypoxia is usually assessed by invasive sampling methods. This proof-of-principle retrospective study explores the role of AI-based MRI-derived imaging biomarkers in non-invasively predicting tumour hypoxia in patients with colorectal liver metastases (CLM).