Differential regulation of progranulin derived granulin peptides.

Tingting ZhangHuan DuMariela Nunez SantosXiaochun WuMitchell D PaganLianne Jillian TrigianiNozomi NishimuraThomas ReinheckelFenghua Hu

Published in: Molecular neurodegeneration (2022)

Our results support that the levels of individual granulin peptides are differentially regulated under physiological and pathological conditions and provide novel insights into how granulin peptides function in the lysosome.

Keyphrases

amino acid
transcription factor
fluorescent probe
living cells