Anti-apoptotic effect of dexamethasone in an ototoxicity model.
Jin Ho LeeSe Heang OhTae Ho KimYoon Young GoJae Jun SongPublished in: Biomaterials research (2017)
DEX has a protective effect on GM-induced hair cell loss in neonatal cochlea cultures and the protective mechanism may involve inhibition of the mitochondrial apoptosis pathway. The combination with scaffold technique can improve delivery of DEX into the inner ear to protect GM-induced ototoxicity.