Insulin Resistance and Genetic Risk Predict Liver-Related Outcomes and Death in Nonalcoholic Fatty Liver Disease.

Christopher J Danford Zhenghui Gordon JiangVeikko SalomaaMartti FärkkiläAntti JulaSatu MännistöAnnamari LundqvistLiisa ValstaMarkus PerolaFredrik O Åberg

Published in: Hepatology communications (2019)

A pathophysiologic risk score consisting of insulin resistance and genetic risk predicts incident liver outcomes in NAFLD. Such scores may represent a viable strategy for risk stratification in NAFLD.

Keyphrases

insulin resistance
adipose tissue
type diabetes
high fat diet
metabolic syndrome
genome wide
polycystic ovary syndrome
cardiovascular disease
skeletal muscle
copy number
high fat diet induced
gene expression