The progression rate of spinocerebellar ataxia type 3 varies with disease stage.
Linliu PengYun PengZhao ChenChunrong WangZhe LongHuirong PengYuting ShiLu ShenKun XiaVanessa B LeottiLaura Bannach JardimBeisha TangRong QiuJiang HongPublished in: Journal of translational medicine (2022)
We first confirmed that ICARS progressed as a nonlinear pattern and varied according to different stages in SCA3. In addition to ATXN3 CAGexp, AOga or aging process regulated the progression by interacting with CAGexp.
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