N-acetyl-cysteine reduces the risk for mechanical ventilation and mortality in patients with COVID-19 pneumonia: a two-center retrospective cohort study.

Stelios F AssimakopoulosDiamanto ArethaDimitris KomninosDimitra DimitropoulouMaria LagadinouLydia LeonidouIoanna OikonomouAthanasia MouzakiMarkos Marangos

Published in: Infectious diseases (London, England) (2021)

Oral NAC administration (1200 mg/d) in patients with COVID-19 pneumonia reduces the risk for mechanical ventilation and mortality. Our findings need to be confirmed by properly designed prospective clinical trials.

Keyphrases

mechanical ventilation
respiratory failure
acute respiratory distress syndrome
intensive care unit
clinical trial
cardiovascular events
risk factors
transcription factor
study protocol
open label