IL-33 enhances macrophage release of IL-1β and promotes pain and inflammation in gouty arthritis.

Victor FattoriLarissa Staurengo-FerrariTiago H ZaninelliRubia CasagrandeRene D OliveiraPaulo Louzada-JuniorThiago M CunhaJose C Alves-FilhoMauro M TeixeiraFernando Q CunhaFlavio A AmaralWaldiceu Aparecido Verri

Published in: Inflammation research : official journal of the European Histamine Research Society ... [et al.] (2020)

IL-33 mediates gout pain and inflammation by boosting macrophages production of cytokines upon MSU crystals stimulus.

Keyphrases

chronic pain
oxidative stress
pain management
neuropathic pain
rheumatoid arthritis
adipose tissue