Pediatric Precision Medicine at the National Cancer Center Japan: Prospective Genomic Study of Pediatric Patients with Cancer as Part of the TOP-GEAR Project.
Kayoko TaoFumito YamazakiTakashi KuboKuniko SunamiTadashi KumamotoAyumu ArakawaMasanaka SugiyamaYuko WatanabeMiho NakajimaNami ShirakawaKazuki TanimuraTakafumi KoyamaMakoto HirataKazuki SudoNoriko TanabeTomoko WatanabeTeruhiko YoshidaMayuko KitamiAkihiko YoshidaYasushi YatabeYoshiko NakanoMiki OhiraTakehiko KamijoAtsuko NakazawaMotohiro KatoKoichi IchimuraTakashi KohnoNoboru YamamotoTomoro HishikiHitotshi IchikawaChitose OgawaPublished in: JCO precision oncology (2023)
The implementation of genomic medicine has furthered our understanding of tumor biology and provided new therapeutic strategies. However, the paucity of proposed agents limits the full potential of actionability, emphasizing the significance of facilitating access to targeted cancer therapies.