Incidence and risk factors for acute kidney injury in head and neck cancer patients treated with concurrent chemoradiation with high-dose cisplatin.

Maurice J D L van der VorstElisabeth C W NeefjesElisa C ToffoliJolanda E W Oosterling-JansenMarije R VergeerC René LeemansMenno P KooistraJens VoortmanMaurice J D L van der Vorst

Published in: BMC cancer (2019)

AKI occurred in 69% of patients with LA-SCCHN undergoing CRT with high-dose cisplatin. Long-term renal function was significantly more impaired in patients with AKI. Hypertension and CINV are significant risk factors. Optimizing prevention strategies for CINV are urgently needed.

Keyphrases

high dose
acute kidney injury
risk factors
stem cell transplantation
locally advanced
low dose
chemotherapy induced
blood pressure
rectal cancer
radiation therapy
arterial hypertension