Regulation of the Immune Cell Repertoire in Psoriasis Patients Upon Blockade of IL-17A or TNFα.

Julia Tittes Jennifer Brell Pia Fritz Constanze Jonak Georg Stary Julia Maria Ressler Sarojinidevi Künig Wolfgang Weninger Johannes Stöckl

Published in: Dermatology and therapy (2024)

Our study shows that anti-IL-17A and anti-TNFα therapy rebalances the immune cell repertoire of lesional skin in psoriatic patients but fails to restore the disturbed immune cell repertoire in non-lesional skin.

Keyphrases

end stage renal disease
rheumatoid arthritis
newly diagnosed
ejection fraction
chronic kidney disease
prognostic factors
systemic lupus erythematosus
patient reported outcomes
disease activity
ankylosing spondylitis
cell therapy
replacement therapy