Antioxidant and Anti-Inflammatory Effects of Coenzyme Q10 Supplementation on Infectious Diseases.
Sonia Sifuentes-FrancoDellaneira Carolina Sánchez-MacíasSandra Carrillo-IbarraJuan José Rivera-ValdésLaura Y ZuñigaVirginia Aleyda Sánchez-LópezPublished in: Healthcare (Basel, Switzerland) (2022)
With the appearance of new viruses and infectious diseases (ID) such as COVID-19 in 2019, as well as the lack of specific pharmacological tools for the management of patients with severe complications or comorbidities, it is important to search for adjuvant treatments that help improve the prognosis of infectious disease patients. It is also important that these treatments limit the oxidative and hyperinflammatory damage caused as a response to pathogenic agents, since, in some cases, an inflammatory syndrome may develop that worsens the patient's prognosis. The potential benefits of complementary nutrients and dietary interventions in the treatment of pathological processes in which oxidative stress and inflammation play a fundamental role have been widely evaluated. Coenzyme Q10 (CoQ10) is a supplement that has been shown to protect cells and be effective in cardiovascular diseases and obesity. Additionally, some studies have proposed it as a possible adjuvant treatment in viral infections. Preclinical and clinical studies have shown that CoQ10 has anti-inflammatory and antioxidant effects, and effects on mitochondrial dysfunction, which have been linked to the inflammatory response.
Keyphrases
- infectious diseases
- oxidative stress
- induced apoptosis
- anti inflammatory
- inflammatory response
- sars cov
- early stage
- cardiovascular disease
- end stage renal disease
- type diabetes
- ejection fraction
- newly diagnosed
- dna damage
- diabetic rats
- metabolic syndrome
- insulin resistance
- physical activity
- ischemia reperfusion injury
- chronic kidney disease
- case report
- prognostic factors
- stem cells
- early onset
- risk factors
- body mass index
- bone marrow
- cell cycle arrest
- coronary artery disease
- risk assessment
- patient reported outcomes
- human health
- genetic diversity
- lps induced
- heat shock protein
- cardiovascular risk factors
- drug induced