Nutrient Abundance Signals the Changing of the Seasons by Phosphorylating PER2.
Daniel C LevineRasmus H ReehThomas McMahonThomas Mandrup-PoulsenYing-Hui FuLouis J PtáčekPublished in: bioRxiv : the preprint server for biology (2024)
High fat diet promotes entrainment to summer but inhibits entrainment to winter.Calorie restriction promotes entrainment to winter but inhibits entrainment to summer.PER2-S662 phosphorylation is required for nutritional regulation of seasonal circadian entrainment.Dietary polyunsaturated fatty acids regulate seasonal circadian entrainment.