Familial Mediterranean fever gene variations could trigger VPS16 -associated early-onset dystonia and diabetes mellitus: clinical identification of a family with MEFV and VPS16 genetic variation association.

Yagmur Inalkac GemiciCemal EkiciMelike BatumCenk AkbostanciAhmet KocHatice Mavioglu

Published in: Rheumatology advances in practice (2024)

variation load in this family and the fact that DM occurs at an earlier age suggest that inflammation may cause an early diabetic clinical presentation.

Keyphrases

early onset
late onset
oxidative stress
type diabetes
glycemic control
genome wide
copy number
dna methylation
wound healing
gene expression
adipose tissue
bioinformatics analysis
genome wide identification