20-HETE synthesis inhibition attenuates traumatic brain injury-induced mitochondrial dysfunction and neuronal apoptosis via the SIRT1/PGC-1α pathway: A translational study.
Wenxing CuiXun WuYingwu ShiWei GuoJianing LuoHaixiao LiuLonglong ZhengYong DuPing WangQiang WangDayun FengShunnan GeYan QuPublished in: Cell proliferation (2020)
The inhibition of 20-HETE synthesis represents a novel strategy to mitigate TBI-induced mitochondrial dysfunction and neuronal apoptosis by regulating the SIRT1/PGC-1α pathway.