Association of COVID-19 vaccines ChAdOx1 and BNT162b2 with major venous, arterial, or thrombocytopenic events: A population-based cohort study of 46 million adults in England.
William N WhiteleySamantha H Y IpJennifer A CooperThomas BoltonSpencer J KeeneVenexia M WalkerRachel DenholmAshley AkbariEfosa OmigieSam HollingsEmanuele Di AngelantonioSpiros DenaxasAngela M WoodJonathan A C SterneCathie L M Sudlownull nullPublished in: PLoS medicine (2022)
In this study, we observed increases in rates of ICVT and thrombocytopenia after ChAdOx1-S vaccination in adults aged <70 years that were small compared with its effect in reducing COVID-19 morbidity and mortality, although more precise estimates for adults aged <40 years are needed. For people aged ≥70 years, rates of arterial or venous thrombotic events were generally lower after either vaccine compared with unvaccinated, suggesting that either vaccine is suitable in this age group.
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