The synergistic efficacy of hydroxychloroquine with methotrexate is accompanied by increased erythrocyte mean corpuscular volume.

Muhammad Ruhu Amin ShipaSu-Ann YeohAndrew Embleton-ThirskDev MukerjeeMichael R Ehrenstein

Published in: Rheumatology (Oxford, England) (2021)

Our data provides mechanistic insight into the synergistic clinical benefit of concomitant hydroxychloroquine with methotrexate, boosting the rise in MCV which could serve as a companion biomarker of treatment response.

Keyphrases

high dose
cancer therapy
electronic health record
big data
deep learning