Analytical Methods for Metformin Estimation.

Durgawati PatelPuspendra KumarSwapnil SharmaJaya Dwivedi

Published in: Critical reviews in analytical chemistry (2017)

Metformin is a widely prescribed oral anti-hyperglycemic agent used in the management of non-insulin dependent diabetes mellitus (NIDDM) or type II diabetes. This article accentuates various analytical methods viz. HPLC, HPTLC, spectrophotometric, electrochemical, capillary electrophoresis and LC-MS for the estimation of metformin in pharmaceutical formulations and in biological matrices.

Keyphrases

capillary electrophoresis
type diabetes
glycemic control
mass spectrometry
simultaneous determination
liquid chromatography
ms ms
cardiovascular disease
gold nanoparticles
ionic liquid
tandem mass spectrometry
molecularly imprinted
insulin resistance