Inorganic polyphosphates stimulates matrix production in human annulus fibrosus cells.

Xiangjiang WangRahul Gawri Changbin LeiJoon LeeGwendolyn SowaRita A Kandel Nam N Vo

Published in: JOR spine (2021)

PolyP thus has both anabolic and bioenergetic effects in AF cells, similar to that observed in NP cells. Together, these results suggest polyP as a potential energy source and a metabolic regulator of disc cells.

Keyphrases

induced apoptosis
cell cycle arrest
oxidative stress
endothelial cells
aortic valve