Emergence of plasmid-mediated mcr genes from Gram-negative bacteria at the human-animal interface.
Humera JavedSidrah SaleemAizza ZafarAamir GhafoorAhmad Bin ShahzadHasan EjazKashaf JunaidShah JahanPublished in: Gut pathogens (2020)
The detection of a considerable number of mcr-1 and mcr-2 genes in animals is worrisome, as they are now being detected in clinical pathogens. The acquisition of mcr genes by colistin-susceptible bacteria could leave us in a post-antibiotic era.
Keyphrases
- escherichia coli
- klebsiella pneumoniae
- multidrug resistant
- genome wide
- gram negative
- bioinformatics analysis
- genome wide identification
- endothelial cells
- acinetobacter baumannii
- drug resistant
- crispr cas
- transcription factor
- genome wide analysis
- dna methylation
- induced pluripotent stem cells
- sensitive detection
- label free