Parity reduces mammary repopulating activity but does not affect mammary stem cells defined as CD24 + CD29/CD49fhi in mice.

Genevieve V DallJessica VieusseuxYashar Seyed-RazaviNathan GoddeMandy Ludford-MentingSarah M RussellAlan AshworthRobin L AndersonGail P RisbridgerMark ShackletonKara L Britt

Published in: Breast cancer research and treatment (2020)

Our data show instead that parity impacts on the stem-like activity of cells outside the MaSC population.

Keyphrases

stem cells
induced apoptosis
cell cycle arrest
type diabetes
high fat diet induced
big data
metabolic syndrome
endoplasmic reticulum stress
mesenchymal stem cells
signaling pathway
insulin resistance
skeletal muscle
deep learning