Impact of cyclophosphamide and etoposide on outcome of clear cell sarcoma of the kidney treated on the National Wilms Tumor Study-5 (NWTS-5).

Nita L SeibelYueh-Yun ChiElizabeth J PerlmanJing TianJunfeng SunJames R AndersonMichael L RitcheyPatrick R ThomasJames MiserJohn A KalapurakalPaul E GrundyDaniel M Green

Published in: Pediatric blood & cancer (2018)

The outcome for patients with CCSK treated on NWTS-5 was similar to NWTS-4 and accomplished over a shorter treatment duration. Stage was highly predictive of outcome. Brain metastases occurred more frequently than on NWTS-4. Regimen I showed more benefit for patients with stage I and II disease as compared with higher stages of disease where new therapies are needed.

Keyphrases

brain metastases
small cell lung cancer
clear cell
low dose
newly diagnosed
combination therapy
smoking cessation