Mechanism of RhoA regulating benign prostatic hyperplasia: RhoA-ROCK-β-catenin signaling axis and static & dynamic dual roles.

Shidong ShanMin SuYan LiZhen WangDaoquan LiuYongying ZhouXun FuShu YangJunchao ZhangJizhang QiuHuan LiuGuang ZengPing ChenXinghuan WangMichael E DiSantoYuming GuoXin-Hua Zhang

Published in: Molecular medicine (Cambridge, Mass.) (2023)

Our novel data demonstrated that RhoA regulated both static and dynamic factors of BPH, RhoA-ROCK-β-catenin signaling axis played an important role in the development of BPH and might provide more possibilities for the formulation of subsequent clinical treatment strategies.

Keyphrases

benign prostatic hyperplasia
lower urinary tract symptoms
drug delivery
electronic health record
transcription factor
big data
deep learning
smooth muscle