Impact of fibroblast growth factor receptor 1 (FGFR1) amplification on the prognosis of breast cancer patients.

Ramona ErberMatthias RübnerSimon DavenportSven HaukeMatthias W BeckmannArndt HartmannLothar HäberlePaul GassMichael F PressPeter A Fasching

Published in: Breast cancer research and treatment (2020)

FGFR1 amplification occurs most frequently in patients with luminal B-like BC. The study showed a nonsignificant correlation with the prognosis, probably due to the small sample size. Further research is therefore needed to address the role of FGFR1 amplifications in early BC patients. FGFR2 and FGFR3 amplifications are rare in patients with primary BC.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
nucleic acid
prognostic factors
peritoneal dialysis
binding protein