Diminished Immune Surveillance during Histologic Progression of Intraductal Papillary Mucinous Neoplasms Offers a Therapeutic Opportunity for Cancer Interception.
Sharia HernandezEdwin Roger Parra CuentesNaohiro UraokaXiming TangYu ShenWei QiaoMei JiangShanyu ZhangBarbara MinoWei LuRenganayaki PandurenganCara L HaymakerKajsa AffolterCourtney L ScaifeMichele Yip-SchneiderC Max SchmidtMatthew A FirpoSean J MulvihillEugene Jon KoayHuamin WangIgnacio I WistubaAnirban MaitraLuisa Maren Solis SotoSubrata SenPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2022)
Our findings provide a basis for interception of cystic neoplasia to PDAC, through maintenance of sustained immune surveillance using vaccines and other prevention approaches.